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Unsaturated Aldols as Useful Substrates in Natural Product Synthesis

Furthermore, it is well known that in the base-catalysed self-condensation of acetone, the equilibrium does not favor the aldol, diacetone alcohol (2).



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and diastereo-selectivity in directed aldol reactions of cyclopent-2 ...
Aldol products can undergo syn/anti isomerisation more commonly by reverse aldolisation. In most cases however, reactions are kinetically controlled.
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ABIKO?MASAMUNE Asymmetric Aldol Reaction
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Stereoselective, Directed Aldol Reaction - Harvard
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